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Price Lists for 2023 Projects
The current projects we are working on in 2023 include the following:
- Aspirin production on a pilot plant scale
- Aspirin qualification
- Phenylacetic acid production
- Lab upgrades
As such, this page compiles the price lists of the various analyses done on each of these topics.
Aspirin Pilot Plant Production
Here we can find the price list of reagents needed for large-scale aspirin production:
| Pilot Plant Scale Aspirin Production | ||||||||
| Reagent | Quantity per cycle | Quantity ordered | Price | Reference | ||||
| Salicylic acid | 1013.5 g | 2 kg | $101.64 | Biosynth | Alternatively | 5 kg | $241.40 | Biosynth |
| Acetic anhydride | 2.5 L | 5 L | $238.87 | VWR | ||||
| Sulfuric acid*(*We have 440 mL) | 125 mL | - | - | - | ||||
| Total | $340.51 | |||||||
Aspirin Qualification
Here we can find the price list of chemicals needed for testing:
| Aspirin quality control standard tests according to the Ph.Eur. | |||||||
| Test | Reagent | Quantity per experiment | Quantity ordered | Price | Reference | Missing Apparatus | |
| IR absorption | Potassium bromide | 300-400 mg | IR Spectrophotometer, hydraulic press | ||||
| Color test | Calcium hydroxide | 0.5 g | 500 g | $63.53 | Biosynth | ||
| Color test | 2-Nitrobenzaldehyde solution | 0.05 mL | 0.25 kg | $50.82 | Biosynth | ||
| Appearance of solution | Reference solution B9 | For comparision | 100 mL | $107.70 | Reagecon | ||
| Related substances | Phosphoric acid | HPLC | |||||
| Related substances | Acetonitrile | HPLC | |||||
| Heavy metals | Thioacetamide solution | 1.20 mL | 25 g (19.7 mL) | $69.00 | Sigma | ||
| Heavy metals | Buffer solution | 2 mL | 1 L | $63.49 | Reagecon | ||
| Heavy metals | Lead standard solution | 10 mL of 1 ppm | 100 mL of 100 ppm | $127.42 | Reagecon | Note: needs to be in water | |
| Loss on drying | Diphosphorus pentoxide | Amount depends on size of desiccator | 500 g | $154.00 | Sigma | vacuum desiccator, weighing bottle | |
| Sulphated ash | Silica gel | crucible, muffle furnace, desiccator | |||||
| Assay | Phenolphthalein | As an indicator | 50 g | $44.84 | VWR | ||
| Total | $680.80 | ||||||
Finalized Price List
In order to work according to priorities, the first involves ordering large amounts of salicylic acid and acetic anhydride. As for the aspirin qualification, due to the specific apparatus that is required, we have decided to move forward with conducting a melting point test and therefore purchasing that apparatus. As for the remaining tests, those will be done at specialized laboratories, such as the university labs listed by the MOPH in order to register and certify a drug. In addition, this table includes components that are missing from the lab but are vital to the projects we are conducting, both now and in the future. Finally, we have also included the reagents required for phenylacetic acid production.
| Title | Reagent | Quantity ordered | Price | Reference | Total |
| Aspirin production | Acetic anhydride | 5 L | $150.00 | VTC (VWR)/in stock | $150.00 |
|
Lab Equipment
|
Separatory funnel (1000 mL) | $32.00 | VTC |
$713.00
|
|
| Complete Buchner filtration apparatus (1000 mL) | $150.00 | VTC | |||
| Stand | $16.00 | VTC | |||
| Capillary tubes | 100 units | $5.00 | VTC | ||
| Separatory funnel (500 mL) | $20.00 | City Med Lab | |||
| Safety goggles | 3 units | $18.00 | City Med Lab | ||
| Fire Extinguisher | 2 kg | $12.00 | |||
| Distillation (Vacuum) | $90.00 | Amazon | |||
| Shipping: | $40.00 | ||||
| Melting point apparatus | $200.00 | Alibaba | |||
| Shipping: | $130.00 | ||||
|
PAA production
|
Methyphenyl acetate | 1 kg | $210.00 | VTC |
$357.00
|
| Sodium hydroxide (2M) | 1 kg | $5.00 | |||
| Ether | 2.5 L | $125.00 | VTC | ||
| Na2SO4 | 1 kg | $17.00 | VTC | ||
| Total | $1,220.00 | $1,220.00 |